Scientist, Sequencing Job Description
Scientist, Sequencing Duties & Responsibilities
To write an effective scientist, sequencing job description, begin by listing detailed duties, responsibilities and expectations. We have included scientist, sequencing job description templates that you can modify and use.
Sample responsibilities for this position include:
Scientist, Sequencing Qualifications
Qualifications for a job description may include education, certification, and experience.
Education for Scientist, Sequencing
Typically a job would require a certain level of education.
Employers hiring for the scientist, sequencing job most commonly would prefer for their future employee to have a relevant degree such as Bachelor's and Master's Degree in Molecular Biology, Biochemistry, Biology, Microbiology, Engineering, Education, Genetics, Science, Biotechnology, Health Sciences
Skills for Scientist, Sequencing
Desired skills for scientist, sequencing include:
Desired experience for scientist, sequencing includes:
Scientist, Sequencing Examples
Scientist, Sequencing Job Description
- Designs and executes method development/validation and/or extractable/leachable studies independently and interprets and reviews analytical data for self and others OR designs and executes multiple stability and inhalation procedures assists others in performing routine maintenance and troubleshooting on multiple instruments (HPLC, GC, UPLC, ICP-MS, LC/MS, GC/MS ) and multiple detection techniques (UV, FL, CAD, ELSD, IC ), methods and procedures
- Routinely acts as the technical project leader for multiple projects, provide updates, reviews and evaluates data, writes reports and proto
- Design & analysis of single molecule experiments utilizing Genia’s proprietary sequencing platform to answer polymerase related questions that affect accuracy and sequencing rate
- Execute process verification and/or optimization studies, including data generation, analysis, and reporting to key stake holders
- Create user guides, training documentation, and marketing collateral related to automated NGS solutions
- Provide automation-related technical expertise as a member of a cross-functional product development and support team
- Install liquid handling protocols at customer sites
- Build and maintain positive relationships with major liquid handler vendor support teams
- Lead projects with customer who have unique automation needs
- Remain current on existing and future liquid handler usage
- Master’s in Molecular Biology or related field AND at least 10 years of relevant experience
- Ability to multitask and learn new methods and technologies as necessary to meet business needs
- Demonstrated ability to work with tight deadlines in a dynamic environment
- Ability to lead, manage, and prioritize multiple projects through completion
- Demonstrated history of developing innovative solutions
- PhD in Molecular Biology or a related field
Scientist, Sequencing Job Description
- Advise R&D about volumes, temperatures, and techniques that are appropriate for automation customers
- Develop and validate automation friendly techniques
- Coordinate automation support activities with other reagent manufacturers and collaborators
- Perform on-site software installations, qualification, training, and service visits as needed
- Provide NGS-focused, automation-related technical expertise as a member of a cross-functional product development team
- Know the organization's Quality Policy and Objectives and comply with it in practice and approach
- Initiate, direct and execute pre-regulatory scientific research and/or development through managing individual studies
- Take a leadership role in projects and guide technical areas independently
- Work closely with scientific, bioinformatics, engineering, software and commercial teams to develop, transfer, and sustain new products
- Manage goals within defined target time frames and make decisions regarding the goals and progress of project teams
- Previous experience creating sequencing libraries for Pacific Biosciences and/or Oxford Nanopore sequencers
- Previous experience extracting high quality nucleic acids from diverse biological samples
- Previous experience performing bioinformatics analyses on single molecule sequencing data using GUI’s or directly in Linux/Unix systems
- Previous experience with LabWare LIMS and operating under a quality management system (ISO)
- Experience with in a regulated laboratory preferred
- Broad knowledge of protein and peptide chemistry, biochemistry, and practical experience in testing (ELISA, Gel Electrophoresis, Peptide Mapping, Amino Acid Analysis)
Scientist, Sequencing Job Description
- Experimental design input for research clinical studies
- Initiate, design and execute product development studies including feasibility, optimization and V&V
- Exercise independent judgment in developing assays, products, processes and performance evaluation criteria
- Solve complex development challenges independently and quickly
- Work closely with bioinformatics, software, operations and commercial teams to develop, transfer, and sustain new products
- May assist in preparing summaries, memos, internal reports, presentations, manuscripts
- Devise and perform suite of experiments to understand membrane formation mechanism and interaction with various chip surfaces
- Develop chip preparation protocol to enable sequencing experiments
- Drive chip efficient up through better understanding of membrane/nanopore failure modes and protocol refinements
- Become an expert in membrane and nanopore formation
- Excellent attention to detail and ability to perform delicate manual tasks in a laboratory
- Strong communication skills (able to clearly communicate problems, protocols, and results to colleagues, both in writing and verbally), and ability to keep complete and detailed records
- Ability to use and/or modify custom written computer scripts
- Full understanding of laboratory requirements, SOPs, ICH guidelines, USP requirements and FDA guidance
- PhD in cancer biology, biochemistry, molecular biology or related field
- 3+ years’ experience in commercial product development
Scientist, Sequencing Job Description
- Data munging and preprocessing
- Statistical analysis of data derived from time series signals
- Create novel analysis pipelines to quantify the prevalence and duration of various sequencing signals
- Provides input to budget and helps to allocate expenditures efficiently for activities individual manages
- Collaborate with software engineers and bioinformatics scientists to set software engineering best practices, including usage of github, Jira, Jenkins, workflow languages
- Overseas operations of different NGS workflows
- Drafts experimental plans, validation reports, work instructions, technology transfer documents, study summaries and SOPs
- Actively participate in internal/external collaboration, portfolio management groups and clinical study and biomarker execution teams
- Work closely with experimentalists to develop analysis tools and automation that will aid in optimization of NGS library preparation protocols
- Work across departments (Production Informatics, Project Management, Quality Assurance, ) to design and validate new lab procedures and diagnostic tests
- The successful candidate should have strong background in molecular biology and microbiology related fields, with hands-on experience in next-generation sequencing assays
- Presents findings or comprehensive project status reviews at internal seminars/meetings
- Serves as an expert resource in a cross-functional team setting (e.g., Manufacturing/Operations, Quality, Marketing, Regulatory Affairs, Clinical Studies, and International Technical Services), provides timely response and follow-ups
- Laboratory experience culturing human and bacterial cells, including purifying DNA from these cells
- Class 2+ biosafety training and clinical lab experience
- Culture of model organisms (C
Scientist, Sequencing Job Description
- Working with pathologists, geneticists, Survey molecular diagnostic landscape to identify current and emerging technologies to assess
- Draft and execute Reports, and Verification Plans and Summaries
- Drive successful transfer of standard operating procedures and tests to Lab Operations team
- Draft and provide content for SOPs
- Strict adherence to local, regulatory, and Quality guidelines to ensure full compliance
- Become an expert on Single Molecule Sequencing Technologies
- Conduct and monitor laboratory experiments utilizing established and published procedures, and technical and theoretical understanding
- Perform sequencing experiments on a daily basis, and interpret the kinetic data
- Optimize polymerase/system performance to meet key metrics
- Development of existing reagent production protocols for RSS nanopore sequencing platform
- Modern DNA sequencing technology
- R/BASH/Python programming, and computing clusters, in relation to genomics and next generation sequencing datasets
- Human genomics and its use in medicine
- Gene expression in mammalian systems
- Optimization of polymerase chain reaction assays
- Fluorescent based biological assays