Biochemist Job Description
Biochemist Duties & Responsibilities
To write an effective biochemist job description, begin by listing detailed duties, responsibilities and expectations. We have included biochemist job description templates that you can modify and use.
Sample responsibilities for this position include:
Biochemist Qualifications
Qualifications for a job description may include education, certification, and experience.
Licensing or Certifications for Biochemist
List any licenses or certifications required by the position: GSK
Education for Biochemist
Typically a job would require a certain level of education.
Employers hiring for the biochemist job most commonly would prefer for their future employee to have a relevant degree such as Bachelor's and Collage Degree in Chemistry, Biochemistry, Biology, Education, Science, Medical Technology, Molecular Biology, Life Sciences, Biotechnology, Microbiology
Skills for Biochemist
Desired skills for biochemist include:
Desired experience for biochemist includes:
Biochemist Examples
Biochemist Job Description
- Candidate will find innovative solutions to challenges posed in developing next-generation ADCs and novel biotherapeutics
- Candidate will participate in the identification, development, and implementation of new technologies/platforms that improve the efficiency of the overall drug-discovery process for therapeutic proteins, especially as related to ADCs
- She/he needs to stay current with applicable internal/external scientific literature and apply new information in innovative ways to successfully complete work assignments
- Drive the development of novel assay methodologies for primary screening and selectivity profiling
- Develop and implement secondary/orthogonal assays to evaluate ligase binders
- Develop and implement E1, E2, E3 binding assays
- Develop and implement in vitro assays to monitor (auto)ubiquitinylation
- Develop and implement assays to determine substrate ubiquitinylation levels
- Perform in-depth mechanistic studies as needed
- Communicate regularly with cross-site teams
- Requires a BS in the life sciences with 2-5 years of relevant lab experience in academia or industry
- Requires minimum of 1 year experience writing technical /scientific reports and 1 year experience generating oral presentations
- Experience in protein expression using mammalian, insect cells and/or E
- Hands on experience using automated protein purification systems such as AKTA or similar instruments
- Experience with protein analytical techniques such as BIAcore, SDS-PAGE, DLS
- Technical know-how of GM research preferably in algae (or in plants), from lab to land (greenhouse/field/pond)
Biochemist Job Description
- Foster and participate in collaborations within and outside of the company
- Actively participate in the publication of primary scientific literature and patents
- Contribute to the intellectual steering of synthetic biology derived activities
- Lead investigation and assay trouble shooting
- Revise product specifications and perform system change procedures
- A background in biocatalysis
- Familiarity in the use of automation and HTS instrumentation is preferable but not necessary
- Assist with laboratory and equipment maintenance laboratory safety
- Writing reports on a monthly basis, oral presentations on a bi-weekly and quarterly basis
- Identify enzymatic systems for assay development
- Clear understanding of GM regulatory and stewardship policies related to trialing, sample movement, labelling, and disposal
- Demonstrated ability to design GM algae/plant trial, performing experiments, analyzing data
- Demonstrated experience of relevant molecular biology techniques
- Masters in related science
- Previous HPLC experience
- Familiarity with USP, JP, Ph
Biochemist Job Description
- Source and characterize raw materials
- Work with team to identify and carry out enzyme conjugation to biological molecules and solid phase supports
- Work with team to establish in-house methodology for enzyme and conjugate characterization
- Work with a cross-functional team on multi-disciplinary projects
- Assist in compendia methods and other analytical method qualification/validation/transfer
- Preparing chemical buffers and protein based matrices
- Requires proficiency with Microsoft Office applications (Word, Excel) and a PC platform
- Evaluation of process equipment to produce custom formulated liquid reagents automated material handling equipment to label and package final product
- Operation of high throughput protein/antibody purification equipment (such as AKTA Pure) in a fast paced work environment
- Utilization of high throughput analytics equipment (such as HPLC) for the collection of protein/antibody quality data
- BS in related science
- Qualifications include a BS/MS with 2-5 years of laboratory experience or Ph
- Strong work ethic, excellent written and communication skills, and the ability to work as a project leader independently
- A minimum of 5-8 years of relevant industry experience in Life Sciences, Medical Devices, or Diagnostics
- Applicant must have diverse experience in purification, bio-conjugation, and biophysical characterization of proteins
- Should be able to analyze, document, and report data concisely and rigorously
Biochemist Job Description
- Documentation of results in official reports, databases and lab notebooks
- Communication of results with upstream and downstream partners, both in written updates and oral presentations
- Protein purification (mAbs, therapeutic proteins, reagent proteins) by affinity or native methods
- Characterize proteins by SDS-PAGE, CGE, Western Blot, and analytical SEC
- This scientist would also demonstrate good laboratory safety awareness and notebook documentation
- Work collaboratively across multiple disciplines, provide strong scientific input
- Develop and optimize analytical screening methods aimed at identifying molecules possessing properties that enable long-term technical success from pre-clinical through clinical development
- Gaining a more comprehensive understanding of in vivo factors affecting capillary and lymphatic uptake of parenterally-administered biotherapeutics
- Apply biochemical principles to the design and development of vitro assays, screening strategies, and mechanism of action studies and deliver high quality screening data to drive SAR support for lead series identification
- Engage and collaborate with multiple disease area teams and make substantial contributions to the conception and execution of experiments including mechanism of action studies and data generation within strict time and quality tolerances
- Should possess excellent communication skills and be proficient in presenting in front of groups
- MS degree with minimum of 5 years, or PhD with minimum of 2 years of industry experience or equivalent required
- Experience working with proteins that have post-translational modifications, in particular glycosylation, is required
- Hands-on experience with protein purification using affinity chromatography, ion exchange chromatography, size exclusion chromatography, reverse phase chromatography is required
- Hands-on experience in operating Waters Alliance HPLC, Agilent 1100/1200 HPLC, Waters Acquity UPLC or equivalent instruments is required
- Demonstrated excellent interpersonal and communication skills are required
Biochemist Job Description
- Independently schedule and prioritize workload to manage several tasks simultaneously
- Work independently while contributing and participating in a team environment
- Assist Senior Scientists with chemical solutions preparation, detailed and complex sample preparation procedures (e.g., digestions, purifications, buffer exchanges ) following SOP’s and established test Protocols
- Test samples to support lot release and stability of clinical trial material method qualification and/or technology transfer
- Perform fermentation based laboratory application tests to produce reliable and precise data that will be utilized to evaluate products performance
- Operate and maintain standard laboratory equipment, for example, laboratory scale fermenters, pipettors, vortex units, temperature blocks, water baths, shaker incubators, autoclaves, HPLC, microscope, spectrophotometer
- Assists with assay validations and routine tests following written protocols
- Partnering with external resources to execute aptamer selection against key targets
- Collaborating with a team of scientists and engineers to integrate aptamer based biosensors into a device for medicine, industry, and sport
- Instigating and implementing hypothesis-driven experiments in aid of efforts to transition basic science discoveries into useful products
- Experience with method development and validation is not required but would be a plus
- Typically a 3 – 5 years’ experience related to immunoassay, clinical chemistry assay preferred
- Candidate should have a strong work ethic, excellent written and communication skills, and the ability to work as a project leader independently
- Bachelor’s degree plus 3-5 years of relevant academic or industry experience or Master’s degree plus 1-2 years experience
- Hands on application of of the techniques listed above and understand their use in the characterization of Biopharmaceuticals
- Experienced with yeast and mRNA display platforms