Scientist Principal Cover Letter

I am excited to be applying for the position of scientist principal. Please accept this letter and the attached resume as my interest in this position.

In the previous role, I was responsible for subject matter expertise on absorption, distribution, metabolism and excretion (ADME) and pharmacokinetic-pharmacodynamic (PK-PD) modeling in support of Discovery projects.

Please consider my qualifications and experience:

• Direct experience with biophysical characterization complex proteins, monoclonal antibodies (e.g., CD, FTIR, DLS, DSC)
• Knowledge of biochemical characterization assays
• PhD in synthetic chemistry (organic, organometallic, inorganic)
• Experience with visualization software (Tableau, MicroStrategy)
• Capture Info/Assess/Make Recommendation
• Performance Data Audit to Ensure Accuracy
• Query Technical Governance Systems/Compile Reports
• Review Data for Completeness/Consistency

I submit this application to express my sincere interest in the scientist principal position.

In my previous role, I was responsible for expertise on dynamic cross-functional teams to define DMPK strategy to achieve target product profiles and provide biologics PK and PK-PD data interpretation.

Please consider my experience and qualifications for this position:

• E- Demonstrated success and effectiveness working in a time-critical production environment
• P- Familiarity with Tableau , BI, Spotfire, or other data visualization software and techniques
• P- Familiarity with other scripting languages ( R, .NET, VBA, JAVA )
• P- Familiarity with Amazon Web Services (Aurora, Lambda, Redshift)
• P- Experience utilizing Atlassian product suite (Bitbucket, Confluence, Jira)
• P- Knowledge of survey sampling methodologies
• P- Knowledge of machine learning and data modeling techniques such as Decision Trees, Random Forests, SVM, Neural Networks, Incremental Response Modeling, and Credit Scoring
• Extensive experience with relational databases, SQL, and/or NoSQL databases

In response to your job posting for scientist principal, I am including this letter and my resume for your review.

In the previous role, I was responsible for model-based quantitative PK/PD data integration to characterize therapeutics exposure and safety/efficacy relationship and to projects its efficacious exposure and dose range in patients.

My experience is an excellent fit for the list of requirements in this job:

• Strong scientific background in pharmacokinetics, pharmacodynamics and drug metabolism sciences
• Experience in writing documentation for regulatory submissions
• Established external scientific reputation
• Excellent communication, mentoring, influencing and leadership skills
• Technical expert in of the area of organic chemistry, enzymatic biotransformation, separation science
• Strong knowledge and industrial hands-on experience in the area of new product development and optimization of structure-activity relationships
• Experience in the development of sweetener ingredients
• Hands on experience in use of enzymes for chemical transformations

Please consider me for the scientist principal opportunity. I am including my resume that lists my qualifications and experience.

In my previous role, I was responsible for pK and PK/PD modeling and simulation to help select lead candidates and optimize dose regimens.

My experience is an excellent fit for the list of requirements in this job:

• Experience with common data science toolkits, such asNumPyorR, etcExcellence in at least one of these is highly desirable
• Experience with data visualization tools, such as D3.js, GGplot,Matplotlib,etc
• Experience with NoSQL databases, such asRedis/ElasticCache,Cassandra, HBase
• Advanced level proficiency with statistical probabilistic modeling techniques such as regression, decision trees, neural networks, support vector machines, supervised/unsupervised clustering techniques
• Expert working within enterprise data warehouse environments platforms (Teradata, Netezza, Oracle, ) and working within distributed computing platforms such as Hadoop and associated technologies such as SQL, HQL, MapReduce, Spark (MLib, SQL, R Py), Storm, Yarn, Kafka, Sqoop and Hive
• Can look at the big picture and handle multiple projects at one time
• Knowledge of data mining and analytic methods such as regression, classifiers, clustering, association rules, decision trees, Bayesian network analysis, Should have expert-level knowledge and experience in of these areas
• Knowledge of and some experience with tools such as Pig, Hive, SparkSQL, , for working with big data in Hadoop and Spark for data extraction and data prep for analysis

In response to your job posting for scientist principal, I am including this letter and my resume for your review.

Previously, I was responsible for advanced quantitative expertise to AstraZeneca projects and researches and recommends appropriate data science solutions, appropriately communicating with a range of stakeholders.

I reviewed the requirements of the job opening and I believe my candidacy is an excellent fit for this position. Some of the key requirements that I have extensive experience with include:

• Experience with permitting and compliance in the chemicals sector
• Tech lead experience and independent ownership of a problem space
• Relevant experience/training in epidemiology or closely related fields
• Extensive experience in successful direction of large epidemiologic projects
• Broad knowledge and experience in the application of epidemiologic approaches to problems in the pharmaceutical or biotechnology industry
• Record of substantial research publications in peer-reviewed journals
• PhD in Computer Science, Engineering, Statistics or a related field
• Knowledge in Information Extraction, Semantic Web, Machine Learning, Deep Learning, Natural language processing, and Statistics