Scientist, Immuno Cover Letter

I submit this application to express my sincere interest in the scientist, immuno position.

In the previous role, I was responsible for expertise on T cell immunology with emphasis into T cell receptor signaling and structure and function relationship.

Please consider my qualifications and experience:

• Actively interact and work closely with team members to support the development of innovative bioassays
• Work in a diverse team setting and collaborate effectively on complex projects
• Fluency in NGS experiments and data analysis
• Working knowledge of commercial and publicly available biological databases including NCBI, Ensembl, ArrayExpress/GEO, SRA, TCGA, 1000 Genomes )
• Knowledge of immunology, expertise in tumor immunology and/ or T cell biology is highly desirable
• Extensive knowledge in the biology of myeloid cells including macrophages, dendritic cells, and monocytes and their influences on adaptive immunity during disease initiation and progression
• Expertise in cellular functional analysis of primary or iPSC-derived immune cells using flow cytometry and cell sorting
• Lab proficiency in such areas as cell culture, transfection, electroporation, viral transduction, western blotting, qRT-PCR, cell imaging, and genomic/epigenomic profiling based on NGS

I would like to submit my application for the scientist, immuno opening. Please accept this letter and the attached resume.

In my previous role, I was responsible for direct contribution to pre-clinical and clinical research with your expertise in genetics & genomics and immunology.

I reviewed the requirements of the job opening and I believe my candidacy is an excellent fit for this position. Some of the key requirements that I have extensive experience with include:

• Creative, innovative and inquisitive personality
• Basic in vivo techniques including mouse handling and tissue harvesting
• Hands-on experience with multi-color FACS immune-phenotyping and standard molecular and cell biology techniques
• Oncology, cancer immunotherapy, molecular biology or human genetics
• Experience in drug development and leading cross-functional teams from discovery to IND is strongly preferred
• Cell line and primary immune cell tissue culture skills
• Familiarity with assays and technologies commonly used to assess immune endpoints (e.g., MLR, antigen-specific T/APC cultures, ELISA, Mesoscale)
• Familiarity with assays and technologies commonly used in cell biology and cell signaling studies, Western blot, immunoprecipitation, Ca flux imaging, receptor-ligand pharmacology

I would like to submit my application for the scientist, immuno opening. Please accept this letter and the attached resume.

In my previous role, I was responsible for scientific expertise and leadership to the immunology team and cross-functionally in support of Alkermes’ preclinical pipeline.

Please consider my experience and qualifications for this position:

• Knowledge in CRISPR/Cas9 technology and its delivery methods including lentiviral vectors and RNPs
• Basic bioinformatic and statistical analytic skills
• Track record of independent research and publication in peer-reviewed journals, including critical reading of literature, hypothesis generation, experimental design and testing, data interpretation, problem solving, and project management
• Experience with regulatory work environment such as GLP, GMP or related preferred
• Proficiency on technical operating systems and proven problem solving and troubleshooting abilities
• Experience in cellular assay development, tissue culture, primary human and mouse cell culture, RT-PCR or Nanostring, flow cytometry heavily preferred
• Leadership experience in the use of innovative molecular and cellular methods to aid drug discovery efforts and a proven track record of critical contributions to drug development pipelines in immunology/immune-oncology
• Proven track record in working in effective cross site multi-functional teams

In response to your job posting for scientist, immuno, I am including this letter and my resume for your review.

In my previous role, I was responsible for expertise and guidance on T cell immunology including isolation and expansion of autologous and cryopreserved allogeneic primary T cell populations.

My experience is an excellent fit for the list of requirements in this job:

• Team leader and team player with strong people skills
• Experience in working with CROs to effectively outsource research and development needs
• Proven scientific track record documented by publications in high-ranking journals
• Research experience and knowledge of immune-oncology and oncology from top-level research institute or industry
• A subject matter expert with a high level of creativity
• Leader that will inspire and engage staff and colleagues across R&D
• Excellent in establishing trustful relationships, and cross-cultural understanding
• Strong, dynamic, ambitious and determined

I would like to submit my application for the scientist, immuno opening. Please accept this letter and the attached resume.

In the previous role, I was responsible for subject matter expertise in immunology and immuno-oncology to internal project teams and committees as scientific functional lead.

Please consider my qualifications and experience:

• Knowledge of cell and molecular biology is essential, expertise in tumor immunology and lymphocyte biology highly desirable
• Moderate leadership presence and presentations skills
• Proactive / Drive for results
• Proficiency in leading teams and activities
• Advanced knowledge and skills to support program specific data review, trend identification, data interpretation
• Advanced knowledge of Medical Terminology and proficient medical writing skills
• Advanced knowledge of the disease area(s), KOLs, indication(s), compound(s) under study competitor compounds (including MOA, PK/PD, biomarker & safety profile)
• Advanced knowledge of the establishment and operation of data monitoring committees, dose review teams, and independent response adjudication committees